Opportunity Information: Apply for CDC RFA IP22 2203
Tracking the burden, distribution, and impact of Post COVID-19 conditions in diverse populations for children, adolescents, and adults (Track PCC) is a CDC funding opportunity designed to strengthen understanding of post-COVID-19 conditions (PCC) in the United States by building a coordinated surveillance and follow-up effort. PCC, as framed in the announcement, refers to a broad set of new, returning, or ongoing health problems that appear or persist more than four weeks after a person is initially infected with SARS-CoV-2. The overall goal is not only to count and characterize PCC cases, but to study how these conditions affect people over time, how they are distributed across different communities, and what factors make PCC more likely to develop, last longer, or resolve.
The program emphasizes diversity and representativeness, with explicit focus on children, adolescents, and adults across varied populations and settings. Awardees are expected to work in collaboration with state partners, academic institutions, and/or health networks to identify cohorts of people with PCC and follow them longitudinally. This long-term follow-up element is central: the CDC is seeking information that goes beyond one-time snapshots and instead tracks health trajectories, functional impacts, and outcomes over time. In parallel, funded projects are expected to examine risk factors (such as demographic, clinical, and contextual drivers that may increase PCC likelihood or severity) and mitigating factors (such as protective elements, interventions, access to care, vaccination status as applicable, or other influences that may reduce risk or support recovery). The intent is to generate actionable evidence that can inform prevention, clinical guidance, and public health response.
Structurally, the NOFO is organized into two coordinated components. Component A funds up to four surveillance sites that will conduct on-the-ground surveillance and cohort follow-up activities. These sites are meant to serve as the primary data-collection and participant-follow-up hubs, leveraging local or regional infrastructure such as public health systems, healthcare delivery organizations, and research networks. Component B funds one coordinating center site that will support cross-site coordination and consistency. While the announcement summary does not detail every coordinating center responsibility, the coordinating center model typically exists to harmonize methods, support shared protocols, facilitate data standardization, promote comparability across locations, and help integrate findings so that results can be interpreted at a broader national level rather than as isolated local studies.
This opportunity is issued by the Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), specifically within NCIRD, and it uses a cooperative agreement funding mechanism. A cooperative agreement generally indicates substantial federal involvement beyond what is typical for a standard grant, meaning the CDC is likely to collaborate closely with recipients on program direction, technical approaches, and coordination expectations. The activity category is health, and the CFDA (assistance listing) number associated with the program is 93.185.
In terms of funding scale and competitive landscape, the opportunity anticipated making five awards total, aligning with the two-component structure (up to four surveillance sites plus one coordinating center). The listed award ceiling is $2,000,000, indicating the maximum amount expected per award under the program parameters presented in the summary. The opportunity was created on January 5, 2022, with an original closing date of March 7, 2022, and applications were required to be submitted electronically by 11:59 pm Eastern Time on the due date.
Eligibility is broad and designed to accommodate the mix of public health agencies, research institutions, and community-oriented organizations that may be positioned to conduct PCC surveillance and follow-up. Eligible applicants include state, county, and city or township governments; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized governments; public housing authorities/Indian housing authorities; nonprofit organizations both with and without 501(c)(3) status (excluding institutions of higher education in those categories); and other entities as clarified in the opportunity’s additional eligibility text. The eligibility framing signals a desire for partnerships that can reach diverse groups, link to clinical and community data sources, and sustain longitudinal participant engagement.
Overall, Track PCC is aimed at building an organized, multi-site picture of how post-COVID conditions emerge and persist, who is most affected, and what factors influence risk and recovery. By combining local surveillance sites with a single coordinating center, the program is structured to generate more standardized, comparable evidence across different populations and geographies, strengthening the public health understanding of PCC burden and impact across the lifespan.Apply for CDC RFA IP22 2203
- The Department of Health and Human Services, Centers for Disease Control - NCIRD in the health sector is offering a public funding opportunity titled "Tracking the burden, distribution, and impact of Post COVID-19 conditions in diverse populations for children, adolescents, and adults (Track PCC)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.185.
- This funding opportunity was created on Jan 05, 2022.
- Applicants must submit their applications by Mar 07, 2022 Electronically submitted applications must be submitted no later than 1159 pm ET on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $2,000,000.00 in funding.
- The number of recipients for this funding is limited to 5 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Others (see text field entitled Additional Information on Eligibility for clarification), Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Track PCC (CDC) Grant Opportunity FAQs
What is the Track PCC funding opportunity?
Track PCC (Tracking the burden, distribution, and impact of Post COVID-19 conditions in diverse populations for children, adolescents, and adults) is a CDC funding opportunity intended to strengthen U.S. understanding of post-COVID-19 conditions (PCC) by building a coordinated surveillance and longitudinal follow-up effort across multiple sites.
What does "post-COVID-19 conditions (PCC)" mean in this announcement?
In this opportunity, PCC refers to a broad set of new, returning, or ongoing health problems that appear or persist more than four weeks after a person is initially infected with SARS-CoV-2.
What is the main purpose or goal of Track PCC?
The overall goal is to go beyond simply counting cases by characterizing PCC and tracking how these conditions affect people over time, how they are distributed across communities, and what factors influence whether PCC develops, lasts longer, becomes more severe, or resolves.
Is the program focused on any particular age groups?
Yes. The opportunity explicitly emphasizes children, adolescents, and adults, with an intent to understand PCC across the lifespan.
Why does the program emphasize diversity and representativeness?
The program is designed to understand how PCC burden and impact vary across diverse populations and settings, so funded work is expected to capture information that is representative and meaningful across different communities.
What kinds of activities are awardees expected to carry out?
Awardees are expected to identify cohorts of people with PCC and follow them longitudinally. Projects are also expected to examine risk factors and mitigating factors, with the aim of generating evidence that can inform prevention, clinical guidance, and public health response.
What does "longitudinal follow-up" mean in the context of this program?
Longitudinal follow-up means tracking participants over time rather than collecting a single one-time snapshot. The intent is to observe health trajectories, functional impacts, and outcomes as they change over months or longer.
What does the program mean by "surveillance" for PCC?
Within this NOFO, surveillance refers to organized efforts to identify and characterize PCC cases and to track burden and distribution in populations, paired with follow-up to understand impacts and outcomes over time.
What types of partners are applicants expected to collaborate with?
Awardees are expected to work in collaboration with state partners, academic institutions, and/or health networks to identify cohorts and support follow-up.
What kinds of factors are projects expected to study as PCC risk factors?
The announcement highlights examining demographic, clinical, and contextual drivers that may increase the likelihood of PCC or influence severity.
What are "mitigating factors" in this NOFO?
Mitigating factors are influences that may reduce PCC risk or support recovery. Examples mentioned include protective elements, interventions, access to care, vaccination status (as applicable), and other influences that could reduce risk or improve outcomes.
How is this funding opportunity structured?
The NOFO is organized into two coordinated components: Component A (surveillance sites) and Component B (a coordinating center).
What is Component A?
Component A funds up to four surveillance sites. These sites conduct on-the-ground surveillance and cohort follow-up activities and serve as the primary hubs for data collection and participant follow-up using local or regional infrastructure.
What kinds of infrastructure might Component A sites leverage?
The summary notes that surveillance sites may leverage public health systems, healthcare delivery organizations, and research networks as part of their local or regional infrastructure.
What is Component B?
Component B funds one coordinating center site intended to support cross-site coordination and consistency across the program.
What does the coordinating center do?
The summary indicates that a coordinating center model typically exists to harmonize methods, support shared protocols, facilitate data standardization, promote comparability across locations, and integrate findings so results can be interpreted at a broader national level rather than only as isolated local studies.
How many total awards did the CDC anticipate making?
The opportunity anticipated five awards total: up to four surveillance sites (Component A) and one coordinating center (Component B).
What is the maximum award amount (award ceiling)?
The listed award ceiling is $2,000,000, representing the maximum amount expected per award under the parameters described in the summary.
Who is the issuing agency?
The opportunity is issued by the Department of Health and Human Services (HHS), Centers for Disease Control and Prevention (CDC), specifically within NCIRD.
What type of funding mechanism is used?
This opportunity uses a cooperative agreement funding mechanism.
What does a cooperative agreement imply for how the CDC works with recipients?
A cooperative agreement generally indicates substantial federal involvement beyond what is typical for a standard grant. In this case, the summary suggests the CDC is likely to collaborate closely with recipients on program direction, technical approaches, and coordination expectations.
What is the activity category for this opportunity?
The activity category is health.
What is the CFDA/Assistance Listing number for Track PCC?
The CFDA (Assistance Listing) number associated with the program is 93.185.
When was this opportunity created and when did it close?
The opportunity was created on January 5, 2022. The original closing date was March 7, 2022.
How were applications required to be submitted and by what time?
Applications were required to be submitted electronically by 11:59 pm Eastern Time on the due date.
Who was eligible to apply?
Eligibility included a broad range of entities: state, county, and city or township governments; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized governments; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories); and other entities as clarified in the opportunity's additional eligibility text.
Does the eligibility language suggest a preference for any particular approach?
The eligibility framing signals an interest in partnerships that can reach diverse groups, connect to clinical and community data sources, and sustain longitudinal participant engagement.
What kind of evidence is the program trying to produce?
The intent is to generate actionable evidence that can inform prevention strategies, clinical guidance, and public health response related to PCC.
What is the overall vision of Track PCC across the U.S.?
By combining multiple surveillance sites with a single coordinating center, Track PCC is structured to build a more standardized and comparable picture of how PCC emerges and persists, who is most affected, and what factors influence risk and recovery across different populations and geographies.
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