Opportunity Information: Apply for PA 18 928

The Innovative Technologies for HIV Behavioral and Social Science Research funding opportunity (PA 18-928) is a National Institutes of Health (NIH) Small Business Innovation Research (SBIR) grant program run through the National Institute of Mental Health (NIMH), specifically aligned with priorities from NIMH's Division of AIDS Research. Its central purpose is to help small businesses create and refine technology that can meaningfully strengthen HIV prevention and treatment efforts, especially when those efforts depend on behavioral and social science research. In practical terms, the program is meant to push forward tools and platforms that improve how HIV-related behaviors are understood, measured, influenced, and supported in real-world settings, including technologies that make interventions more scalable, engaging, or effective.

This opportunity is structured as an SBIR award using the R43/R44 mechanisms, which are commonly associated with early-stage and follow-on small business research and development. The "Clinical Trial Optional" label signals that projects may include a clinical trial if it is appropriate for the technology being developed, but a trial is not automatically required. The overall emphasis is on innovation and development: either building entirely new technologies for HIV prevention or treatment, or adapting existing technologies so they can be applied in more powerful or practical ways to HIV behavioral and social science research questions. That can include technology that supports intervention delivery, data collection, adherence support, risk reduction, behavior change, patient engagement, provider workflows, or other technology-enabled strategies that improve outcomes along the HIV prevention and care continuum.

Eligibility is tightly focused on small businesses, which are the intended applicants under the SBIR program. Foreign institutions (non-U.S. entities) are not eligible to apply, and non-U.S. components of U.S. organizations are also not eligible to apply. However, the announcement notes that "foreign components" may be permitted under NIH policy, meaning certain parts of the work could potentially be conducted outside the United States if they meet NIH requirements and are allowed under the NIH Grants Policy Statement. This typically matters for projects where relevant populations, implementation settings, collaborators, or field testing opportunities are located internationally, but the applicant organization itself must still be an eligible U.S. small business.

Administratively, the opportunity is categorized as a discretionary grant in the health area, listed under CFDA 93.242. The funding opportunity was created on September 19, 2018, and the original closing date shown in the source data is September 5, 2021. The listing does not provide an award ceiling or expected number of awards, so applicants would generally need to consult NIH SBIR budget guidance and the full announcement for current caps, phased budget expectations, and review considerations. Overall, the program is best understood as a targeted NIH SBIR pathway for small businesses to turn promising technology ideas into tested, usable products or platforms that improve HIV prevention and treatment by leveraging behavioral and social science research approaches.

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Innovative Technologies for HIV Behavioral and Social Science Research (R43/R44 Clinical Trial Optional)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242.
  • This funding opportunity was created on 2018-09-19.
  • Applicants must submit their applications by 2021-09-05. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Small businesses.
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