Opportunity Information: Apply for CDC RFA CK 26 0193
The Centers for Disease Control and Prevention (CDC), through NCEZID, is offering a discretionary cooperative agreement to strengthen national awareness and practical knowledge of Alpha-gal Syndrome (AGS) in the United States. AGS is an emerging allergy condition linked to tick bites and is currently not a nationally notifiable disease, which means consistent reporting and standardized visibility are limited across jurisdictions. This funding opportunity is designed to close those gaps by improving how AGS is recognized, tracked, and managed, while also expanding what the public and healthcare providers understand about risks, symptoms, and prevention.
The grant is organized around three connected strategies: SHARE, EDUCATE, and TRACK. Under SHARE, recipients are expected to build or strengthen a network of AGS professionals and partners who can rapidly share up-to-date information across key stakeholder groups. That includes public health agencies, academic researchers, clinicians, and advocacy organizations. The intent is to create a reliable mechanism for exchanging emerging evidence and practice-based lessons so that patient care improves and public health agencies can respond more effectively as AGS patterns shift over time.
Under EDUCATE, the focus is on developing and distributing communications that meet people where they are. This includes materials for the general public, individuals living with AGS, and groups with higher likelihood of tick exposure such as outdoor workers, hikers and hunters, dog owners, and others who spend time in tick habitats. The opportunity also places strong emphasis on healthcare provider education, supporting the creation of clinical training and practical resources that can help providers recognize AGS, consider it during differential diagnosis, and guide patients on management and prevention. In practice, this strategy is meant to reduce delayed diagnosis, improve clinical decision-making, and make information more accessible and actionable for those at risk.
TRACK addresses the surveillance challenge directly by supporting active or enhanced public health surveillance for AGS. Because AGS is not nationally notifiable, this funding encourages approaches that improve situational awareness through targeted data collection, case-finding, or other surveillance enhancements. The NOFO highlights that these efforts may be especially valuable in patient populations or geographic areas where access to specialized providers is limited, suggesting an equity-oriented interest in reaching communities that might otherwise be underdiagnosed or underrepresented in available data.
This opportunity is issued as a cooperative agreement, meaning awardees should expect substantial involvement from CDC compared with a standard grant, often including collaboration on strategy, technical assistance, and alignment with federal public health priorities. The funding opportunity is titled "Increasing awareness and knowledge of Alpha-gal Syndrome in the United States" (Funding Opportunity Number: CDC-RFA-CK-26-0193) and is listed under CFDA 93.084. The application deadline is July 9, 2026. The award ceiling is $1,000,000, and CDC anticipates making approximately three awards.
Eligibility is broad and includes state, county, and local governments; special district governments; independent school districts; public and private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (excluding institutions of higher education in those categories); for-profit organizations other than small businesses; small businesses; and unrestricted applicants more generally. The NOFO also notes that bona fide agents may apply, referencing CDC guidance on using administrative partners to expedite the federal grant process. Overall, the opportunity is aimed at building a more connected professional ecosystem around AGS, improving public and clinical education, and generating better surveillance data to inform patient care and public health action.Apply for CDC RFA CK 26 0193
- The Centers for Disease Control - NCEZID in the health sector is offering a public funding opportunity titled "Increasing awareness and knowledge of Alpha-gal Syndrome in the United States" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.084.
- This funding opportunity was created on 2026-05-19.
- Applicants must submit their applications by 2026-07-09. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,000,000.00 in funding.
- The number of recipients for this funding is limited to 3 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Unrestricted.
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Frequently Asked Questions (FAQs)
What is this funding opportunity?
This is a CDC discretionary cooperative agreement (issued through NCEZID) focused on strengthening national awareness and practical knowledge of Alpha-gal Syndrome (AGS) in the United States. The opportunity is titled "Increasing awareness and knowledge of Alpha-gal Syndrome in the United States."
What is Alpha-gal Syndrome (AGS) and why is it a focus of this grant?
AGS is described in the notice as an emerging allergy condition linked to tick bites. The opportunity emphasizes that AGS is currently not a nationally notifiable disease, which limits consistent reporting and standardized visibility across jurisdictions, creating gaps this grant aims to address.
Why does it matter that AGS is not a nationally notifiable disease?
Because AGS is not nationally notifiable, the notice indicates that consistent reporting and standardized visibility are limited across jurisdictions. This makes it harder to recognize patterns, compare data, and maintain shared situational awareness nationwide.
What are the main goals of the program?
Based on the description, the program is designed to close gaps in how AGS is recognized, tracked, and managed, while expanding what the public and healthcare providers understand about AGS risks, symptoms, and prevention.
What are the three strategies supported by this opportunity?
The grant is organized around three connected strategies: SHARE, EDUCATE, and TRACK.
What does the SHARE strategy involve?
Under SHARE, recipients are expected to build or strengthen a network of AGS professionals and partners to rapidly share up-to-date information across stakeholder groups. The notice specifically mentions public health agencies, academic researchers, clinicians, and advocacy organizations, with the intent of improving patient care and helping public health agencies respond as AGS patterns shift over time.
Who are the key stakeholders expected to be part of the SHARE network?
The opportunity calls out public health agencies, academic researchers, clinicians, and advocacy organizations as examples of key stakeholder groups for rapid information sharing.
What does the EDUCATE strategy focus on?
EDUCATE centers on developing and distributing communications that "meet people where they are." This includes materials for the general public, individuals living with AGS, and groups with higher likelihood of tick exposure, as well as strong emphasis on healthcare provider education.
Which audiences are specifically mentioned for public-facing education materials?
The notice mentions the general public, individuals living with AGS, and groups with higher likelihood of tick exposure such as outdoor workers, hikers and hunters, dog owners, and others who spend time in tick habitats.
How does the opportunity address healthcare provider education?
The opportunity emphasizes healthcare provider education by supporting the creation of clinical training and practical resources to help providers recognize AGS, consider it during differential diagnosis, and guide patients on management and prevention. The stated intent includes reducing delayed diagnosis, improving clinical decision-making, and making information more accessible and actionable.
What is the TRACK strategy and what problem is it trying to solve?
TRACK supports active or enhanced public health surveillance for AGS. Because AGS is not nationally notifiable, the funding encourages approaches that improve situational awareness through targeted data collection, case-finding, or other surveillance enhancements.
Does the notice suggest where enhanced surveillance could be especially valuable?
Yes. The NOFO highlights that surveillance efforts may be especially valuable in patient populations or geographic areas where access to specialized providers is limited, signaling an equity-oriented interest in reaching communities that might otherwise be underdiagnosed or underrepresented in available data.
What type of award is this (grant vs. cooperative agreement)?
This opportunity is a cooperative agreement. The description notes that awardees should expect substantial involvement from CDC compared with a standard grant, including collaboration on strategy, technical assistance, and alignment with federal public health priorities.
What is the Funding Opportunity Number (NOFO number)?
The Funding Opportunity Number is CDC-RFA-CK-26-0193.
What is the CFDA listing for this opportunity?
The opportunity is listed under CFDA 93.084.
When is the application deadline?
The application deadline is July 9, 2026.
What is the maximum award amount?
The award ceiling is $1,000,000.
How many awards does CDC expect to make?
CDC anticipates making approximately three awards.
Who is eligible to apply?
Eligibility is broad and includes: state, county, and local governments; special district governments; independent school districts; public and private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (excluding institutions of higher education in those categories); for-profit organizations other than small businesses; small businesses; and unrestricted applicants more generally.
Are tribal governments and tribal organizations eligible?
Yes. The eligible applicant types listed include federally recognized tribal governments and other tribal organizations.
Are nonprofits eligible even if they do not have 501(c)(3) status?
Yes. The eligibility list includes nonprofits with or without 501(c)(3) status (with the noted exclusion for institutions of higher education in those nonprofit categories).
Are for-profit organizations eligible?
Yes. The eligibility list includes for-profit organizations other than small businesses, and also includes small businesses.
What does it mean that "bona fide agents" may apply?
The NOFO notes that bona fide agents may apply and references CDC guidance on using administrative partners to expedite the federal grant process. This indicates that, in some cases, an administrative or partner entity may apply on behalf of an eligible organization, consistent with CDC guidance.
What overall outcomes is CDC aiming for with this opportunity?
From the description provided, CDC aims to build a more connected professional ecosystem around AGS, improve public and clinical education, and generate better surveillance data to inform patient care and public health action.
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