Opportunity Information: Apply for PA 20 201

The Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Basic Experimental Studies with Humans Required) is a National Institutes of Health (NIH) career development grant designed to help clinically trained professionals become independent, research-focused investigators. The central goal is to build a strong pipeline of clinician-scientists whose work can meaningfully address the nations health-related research needs. It does this by providing structured, mentored research training and, importantly, dedicated protected time so early-career investigators with clinical doctoral degrees can focus intensively on research rather than having research time continually displaced by clinical or other duties. The program supports development in biomedical and behavioral research areas, including translational research that bridges foundational discoveries and clinical application.

This particular K08 parent announcement is specific to projects that include independent basic experimental studies with humans required. In practical terms, that means the supported research is expected to involve human participants in a way that fits NIH definitions for this category of basic research, rather than being purely animal-based, purely in vitro, or limited to secondary analyses without human experimental involvement. Applicants should pay close attention to NIH policy language around human subjects research and the distinction between clinical trials and basic experimental studies with humans, because the funding opportunity title signals that the research plan must align with that expectation and the associated application requirements.

The funding opportunity is listed as PA 20-201 and uses the grant funding instrument under a discretionary opportunity category. While the announcement is aimed at individual career development, the application is submitted through an eligible organization on behalf of the candidate. A wide range of applicant organizations can serve as the sponsoring institution, including public and private institutions of higher education, nonprofit organizations (both 501(c)(3) and non-501(c)(3) entities that are not institutions of higher education), for-profit organizations (other than small businesses), small businesses, and multiple layers of government entities such as state, county, city or township governments, special district governments, and independent school districts. It also includes tribal entities (federally recognized tribal governments as well as other tribal organizations) and public housing authorities/Indian housing authorities. NIH also explicitly highlights additional eligible applicant types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), as well as faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions.

At the same time, NIH places clear limits on foreign involvement. Non-domestic (non-U.S.) entities (foreign organizations and foreign institutions) are not eligible to apply as the applicant organization, and non-domestic components of U.S. organizations are not eligible to apply either. However, foreign components are allowed as defined by the NIH Grants Policy Statement, which generally means a U.S. applicant organization may include certain scientifically justified foreign elements within the overall project structure, subject to NIH rules and review considerations.

The opportunity falls under multiple CFDA (now commonly referred to as Assistance Listing) numbers, reflecting that it may be used by different NIH Institutes and Centers depending on scientific area and mission alignment. The listed numbers are 93.113, 93.121, 93.173, 93.213, 93.242, 93.273, 93.279, 93.307, 93.853, 93.865, 93.866, and 93.867. The funding opportunity was created on 2020-05-12, and the original closing date provided in the source information is 2024-05-07. The provided record does not specify an award ceiling or expected number of awards, which typically means applicants need to consult the full NIH announcement and the relevant Institutes and Centers for budget limits, salary and research support caps, project period norms, and the likely level of competition in their scientific area.

Overall, this K08 is best understood as a mentored launchpad for clinicians who want to commit seriously to research. It supports an intensive, supervised career development period in which the candidate builds advanced research skills, produces publishable results, and positions themselves to compete for independent NIH research funding later. The emphasis on protected time and mentorship is the hallmark of the mechanism: NIH is not just funding a project, it is investing in the person and the training environment so the candidate can emerge as a productive, independent clinical scientist working on high-impact questions in human health and disease.

  • The National Institutes of Health in the education, environment, health, income security and social services sector is offering a public funding opportunity titled "Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Basic Experimental Studies with Humans Required)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.173, 93.213, 93.242, 93.273, 93.279, 93.307, 93.853, 93.865, 93.866, 93.867.
  • This funding opportunity was created on 2020-05-12.
  • Applicants must submit their applications by 2024-05-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
Apply for PA 20 201

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Emergency Awards: RADx-UP Coordination and Data Collection Center (CDCC) (U24 Clinical Trial Optional) Apply for RFA OD 20 013

Funding Number: RFA OD 20 013
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BRAIN Initiative: Tools for Germline Gene Editing in Marmosets (U01 - Clinical Trial Not Allowed) Apply for RFA DA 21 006

Funding Number: RFA DA 21 006
Agency: National Institutes of Health
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Fertility Status as a Marker for Overall Health (R01 Clinical Trial Optional) Apply for PAR 20 281

Funding Number: PAR 20 281
Agency: National Institutes of Health
Category: Education, Environment, Health, Income Security and Social Services
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Fertility Status as a Marker for Overall Health (R21 Clinical Trial Not Allowed) Apply for PAR 20 282

Funding Number: PAR 20 282
Agency: National Institutes of Health
Category: Education, Environment, Health, Income Security and Social Services
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Centers to Advance Research in Endometriosis (CARE) (P01 Clinical Trial Not Allowed) Apply for RFA HD 21 002

Funding Number: RFA HD 21 002
Agency: National Institutes of Health
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NIH Blueprint for Neuroscience Research: Functional Neural Circuits of Interoception (R01, Clinical Trial Not Allowed) Apply for RFA AT 21 003

Funding Number: RFA AT 21 003
Agency: National Institutes of Health
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Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Humans Required) Apply for PAR 21 039

Funding Number: PAR 21 039
Agency: National Institutes of Health
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NIH Blueprint for Neuroscience Research: Tools and Technologies to Explore Nervous System Biomolecular Condensates (R21 Clinical Trial Not Allowed) Apply for RFA DA 22 008

Funding Number: RFA DA 22 008
Agency: National Institutes of Health
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Building Interdisciplinary Research Careers in Women's Health Program (BIRCWH) (K12 Clinical Trial Optional) Apply for RFA OD 21 006

Funding Number: RFA OD 21 006
Agency: National Institutes of Health
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NIH Blueprint and BRAIN Initiative Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award (F99/K00 Clinical Trial Not Allowed) Apply for RFA NS 21 012

Funding Number: RFA NS 21 012
Agency: National Institutes of Health
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PHS 2021-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required) Apply for PA 21 261

Funding Number: PA 21 261
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Mobile Health: Technology and Outcomes in Low and Middle Income Countries (R21/R33 - Clinical Trial Optional) Apply for PAR 21 303

Funding Number: PAR 21 303
Agency: National Institutes of Health
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NIH Blueprint for Neuroscience Research Short Courses in Neurotherapeutics Development (R25 Clinical Trial Not Allowed) Apply for RFA NS 21 025

Funding Number: RFA NS 21 025
Agency: National Institutes of Health
Category: Education, Environment, Health, Income Security and Social Services
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Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) Apply for PAR 22 060

Funding Number: PAR 22 060
Agency: National Institutes of Health
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Implementation Research to Reduce Noncommunicable Disease (NCD) Burden in Low- and Middle-Income Countries (LMICs) and Tribal Nations During Critical Life Stages and Key Transition Periods (R01 Clinical Trial Optional) Apply for PAR 22 132

Funding Number: PAR 22 132
Agency: National Institutes of Health
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NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03 Clinical Trial Not Allowed) Apply for PAR 22 160

Funding Number: PAR 22 160
Agency: National Institutes of Health
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Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed) Apply for PAR 22 106

Funding Number: PAR 22 106
Agency: National Institutes of Health
Category: Education, Environment, Health, Income Security and Social Services
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Dissemination and Implementation Research in Health (R21 Clinical Trial Optional) Apply for PAR 22 109

Funding Number: PAR 22 109
Agency: National Institutes of Health
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PHS 2022-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required) Apply for PA 22 179

Funding Number: PA 22 179
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